DEXAMETHASONE-CYCLOPHOSPHAMIDE PULSE THERAPY IN PEMPHIGUS- A CLINICAL STUDY
نویسندگان
چکیده
منابع مشابه
Dexamethasone-cyclophosphamide pulse therapy in pemphigus.
Fifty patients with pemphigus (45 pemphigus vulgaris, 5 pemphigus foliaceus) were treated with dexamethasone-cyclophosphamide pulse therapy. The pulse consisted of 136 mg dexamethasone dissolved in 5% dextrose given in a drip over a period of 1-2 hours on 3 consecutive days. In addition, 500 mg cyclophosphamide was added in the drip on the first day. Such pulses were given at monthly intervals....
متن کاملPulse intravenous cyclophosphamide therapy in pemphigus.
BACKGROUND Adjuvant therapy is commonly used in pemphigus to mitigate the high morbidity and mortality associated with the use of corticosteroids and improve disease control. However, these adjuvant agents are not without adverse effects of their own, including an increased risk of malignancy with the use of oral immunosuppressives. Intravenous pulse cyclophosphamide, which may be more efficaci...
متن کاملSystemic sclerosis and dexamethasone cyclophosphamide pulse therapy.
Sir, There have been quite a few instances where the physician or may be even a dermatologist (mis) advices a patient having systemic sclerosis that there is no satisfactory treatment for this disease, as has also been done in the paper Therapeutic trials for systemic sclerosis: An update by Sardana and Garg.[1] Such patients often feel frustrated and disappointed, till another dermatologist ...
متن کاملDexamethasone cyclophosphamide pulse therapy: some suggestions for modifications.
Sir, It was truly enlightening and educative reading the editorial on dexamethasone pulse therapy in dermatology and the associated viewpoint by Prof. Pasricha who is widely regarded as the father of pulse therapy in India. Pulse therapy has altered the management and outcome of autoimmune diseases in general and pemphigus in particular. It has slowly but surely replaced the conventional dosing...
متن کاملDexamethasone cyclophosphamide pulse therapy in systemic lupus erythematosus: a case report.
OBJECTIVE To put systemic lupus erythematosus (SLE) in remission for a prolonged period. METHODS Dexamethasone cyclophosphamide pulse (DCP) therapy was used in a 40-year-old female with SLE of 3 years' duration. DCP therapy comprises an intravenous infusion of 100 mg dexamethasone in 500 ml of 5% glucose over 1-1(1/2) hours on 3 consecutive days along with cyclophosphamide 500 mg in the same ...
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ژورنال
عنوان ژورنال: Journal of Evidence Based Medicine and Healthcare
سال: 2019
ISSN: 2349-2562,2349-2570
DOI: 10.18410/jebmh/2019/225